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黄珊

发布者:黄珊 [发表时间]:2016-09-23 [来源]:化学与材料科学学院 [浏览次数]:

 

 

 

学历、职称博士、教授,硕士生导师(分析化学、无机化学、学科教学(化学))

研究方向:新型多功能纳米光/电化学生物传感器

兼职:中国化工学会专家库专家;广西化学化工学会理事;中国化学会会员;国家及省级科技项目评审专家;南宁师范大学第十届学术委员会委员

电话:0771-3908065

Emailhuangs@nnnu.edu.cn

教育与研究经历

2000.92004.7 武汉大学应用化学专业,获理学学士学位;

2004.92009.7 武汉大学分析化学专业,获理学博士学位(硕博连读);

2009.82011.10 加拿大魁北克大学国家科学研究院,博士后;

2018.72019.7 美国内布拉斯加大学林肯分校,访问学者,国家留学基金管理委员会西部地区人才培养特别项目;

2019.92020.1 武汉大学化学与分子科学学院,访问学者,广西高等学校千名中青年骨干教师培育计划项目;

201110月至今 信誉好的网投平台,硕士生导师(20131月),副教授(201612月),教授(201912月)。

教学情况

主讲《分析化学》、《仪器分析》、《分析化学实验》和《仪器分析实验》等本科生专业课,《现代分子光谱》和《生物分析化学》等研究生学位课。指导本科生获广西高校化学化工类论文及设计竞赛一等奖4项、二等奖1项,指导本科生获“挑战杯”广西大学生课外学术科技作品竞赛二等奖和三等奖各1项。指导本科生获国家级大学生创新创业计划项目6项、自治区级大学生创新创业计划项目6项。指导研究生获自治区级研究生创新项目3项,获研究生国家奖学金7人、自治区优秀毕业研究生2人。

科研情况

主要从事新型多功能纳米光/电化学生物传感器的高效构筑和生物分析应用研究。主持国家级和省部级科研项目7项,参与国家级科研项目10余项。以第一作者或通讯作者在国际权威学术期刊上发表学术论文60余篇,其中中科院大类一区论文10篇,二区论文22篇,被世界知名学者在包括Chem. Rev., Chem. Soc. Rev., Coordin. Chem. Rev., J. Am. Chem. Soc., Small, Trac-Trend Anal. Chem., Carbon, Anal. Chem., Chem. Commun., Biosens. Bioelectron., Nanoscale, Biomaterials等国际顶级学术期刊正面评价和引用1500余次,其中单篇最高引用160余次,一篇论文被列为ESI高被引论文。申请国家发明专利100余件,获授权60余件,转让50余件。受邀为Anal. Chem., ACS Appl. Mater. Interfaces, Nanoscale, Chem. Commun., Biosens. Bioelectron., Carbon, J. Mater. Chem. A, Electrochim. Acta20余个国际著名SCI学术期刊评审相关稿件,作为评审专家评审广西科技项目10和宁夏科技项目18,在该领域的研究积累和工作基础得到国内外同行的认可与好评。

2015年入选广西高校青年教师教学业务能力提升计划第二期培养对象。

2018年入选广西高等学校千名中青年骨干教师培育计划第一期培养对象

获奖情况

12021年获广西科学技术奖自然科学三等奖

22019年获第八届广西青年学术年会论文二等奖2

32019年获广西高等教育自治区级教学成果二等奖

42018年获广西科学技术奖自然科学三等奖

52017年获广西高等教育自治区级教学成果二等奖

62018年获广西师范学院第二届“教学新秀奖”

72017年获广西师范学院本科教学审核评估先进个人

82016年获广西师范学院高等教育校级教学成果一等奖

92016年获广西师范学院科研工作先进个人

102015年获广西师范学院科研工作先进个人

112014-2015学年度广西师范学院教学工作优秀奖

122013-2015学年度广西师范学院“优秀教师”

132015年获广西师范学院“优秀班主任”

142013年获广西师范学院“优秀班主任”

152011-2012年学年度广西师范学院教学工作优秀奖

主持承担科研项目

1、国家自然科学基金项目,基于靶向近红外碳量子点纳米生物传感器的构筑及其超高灵敏识别病毒核酸的应用基础研究。

2、国家自然科学基金项目,基于生物热力学方法的芳杂环甾体抗肿瘤药物与端粒DNA相互作用机制研究。

3、第46批教育部留学回国人员科研启动基金项目,量子点FRET化学传感器用于有机磷农药残留可视化原位检测。

4、广西自然科学基金重点项目,近红外碳量子点纳米生物传感器的构建及其对生物标志物的超高灵敏检测新方法研究。

5、广西科学研究与技术开发计划项目,饮用水中工业化学污染物靶向性高灵敏检测新技术与方法研究。

6、广西自然科学基金面上项目,基于芳基钌靶向抗肿瘤药物与端粒DNA 相互作用机制研究。

7、广西自然科学基金青年基金项目,基于海洋天然活性成分的甾体酰胺类抗肿瘤药物与端粒DNA相互作用机制研究。

8、广西高等教育本科教学改革工程项目一般A类,基于“翻转课堂”理念的高师化学教学改革与实践研究。

9、广西高校科研项目,基于海洋天然活性成分的甾体酰胺类抗肿瘤药物与端粒DNA相互作用机制研究。

主要学术论文* 通讯作者

2021

1. Shan Huang, Huajian Luo, Wei Su, Qi Xiao*, Jiangning Xie*. Comparative study of binding interactions between three organometallic rhodium(III) complexes with curcuminoid ligands and human serum albumin. Journal of Molecular Recognition 2021, 34, e2876.

2. 罗华健, 李海梅, 肖琦, 黄珊*, 刘义*. 三种不同元素掺杂的碳点与DNA相互作用及其机制研究. 中国科学:化学 2021, 51, 74−84.

2020

1. Shan Huang, Haimei Li, Yi Liu, Liyun Yang, Dan Wang, Qi Xiao*. Investigations of conformational structure and enzymatic activity of trypsin after its binding interaction with graphene oxide. Journal of Hazardous Materials 2020, 392, 122285. (中科院大类一区)

2. Shan Huang, Jiandong Yao, Xu Chu, Gan Ning, Zhiqiang Zhou, Yi Liu, Qi Xiao*. A ratiometric fluorescent assay for evaluation of alkaline phosphatase activity based on ionic liquid–functionalized carbon dots. Microchimica Acta 2020, 187, 271. (中科院大类二区)

3. Xu Chu, Gan Ning, Zhiqiang Zhou, Yi Liu, Qi Xiao*, Shan Huang*. Bright Mn-doped carbon dots for the determination of permanganate and L-ascorbic acid by a fluorescence on-off-on strategy. Microchimica Acta 2020, 187, 659. (中科院大类二区)

4. Shan Huang, Haimei Li, Huajian Luo, Liyun Yang, Zhiqiang Zhou, Qi Xiao*, Yi Liu*. Conformational structure variation of human serum albumin after binding interaction with black phosphorus quantum dots. International Journal of Biological Macromolecules 2020, 146, 405−414. (中科院大类二区)

5. Qi Xiao, Jiandan Liang, Huajian Luo, Haimei Li, Jing Yang, Shan Huang*. Investigations of conformational structures and activities of trypsin and pepsin affected by food colourant allura red. Journal of Molecular Liquids 2020, 319, 114359. (中科院大类二区)

6. Jiawen Li, Xiaoyu Jin, Mengmeng Feng, Shan Huang*, Jinrong Feng*. Ultrasensitive and highly selective electrochemical biosensor for HIV gene detection based on amino-reduced graphene oxide and β-cyclodextrin modified glassy carbon electrode. International Journal of Electrochemical Science 2020, 15, 2727−2738.

7. Haimei Li, Huajian Luo, Qi Xiao, Liyun Yang, Shan Huang*, Yi Liu*. Investigations of interactions and mechanisms of chiral graphene quantum dots with DNA. Acta Chimica Sinica 2020, 78, 577586.

8. Shan Huang, Huajian Luo, Yi Liu, Wei Su, Qi Xiao*. Comparable investigation of binding interactions between three arene ruthenium(II) thiosemicarbazone complexes and calf thymus DNA. Polyhedron 2020, 192, 114864.

2019

1. Qi Xiao*, Jiawen Li, Xiaoyu Jin, Yi Liu, Shan Huang*. Ultrasensitive electrochemical microRNA-21 biosensor coupling with carboxylate-reduced graphene oxide-based signal-enhancing and duplex-specific nuclease-assisted target recycling. Sensors and Actuators B: Chemical 2019, 297, 126740. (中科院大类一区)

2. Shan Huang, Jiandong Yao, Xu Chu, Yi Liu, Qi Xiao*, Yue Zhang*. One-step facile synthesis of nitrogen-doped carbon dots: A ratiometric fluorescent probe for evaluation of acetylcholinesterase activity and detection of organophosphorus pesticides in tap water and food. Journal of Agricultural and Food Chemistry 2019, 67, 11244−11255. (中科院大类一区)

3. Qi Xiao, Jinrong Feng, Mengmeng Feng, Jiawen Li, Yi Liu, Dan Wang, Shan Huang*. A ratiometric electrochemical aptasensor for ultrasensitive determination of adenosine triphosphate via triple-helix molecular switch. Microchimica Acta 2019, 186, 478. (中科院大类二区)

4. Shan Huang, Erli Yang, Jiandong Yao, Xu Chu, Yi Liu, Qi Xiao*. Nitrogen, phosphorus and sulfur tri-doped carbon dots are specific and sensitive fluorescent probes for determination of chromium(VI) in waters samples and in living cells. Microchimica Acta 2019, 186, 851. (中科院大类二区)

5. Shan Huang, Erli Yang, Jiandong Yao, Xu Chu, Yi Liu, Yue Zhang, Qi Xiao*. Nitrogen, cobalt co-doped magnetic carbon dots as a ratiometric fluorescence universal platform for cholesterol and uric acid in human blood serum. ACS Omega 2019, 4, 93339342.

6. Erli Yang, Jiandong Yao, Lumin Wang, Yi Liu, Qi Xiao, Shan Huang*. InP/ZnS quantum dot-based fluorescent probe for directly sensitive and selective detection of horseradish peroxidase. Methods and Applications in Fluorescence 2019, 7, 035008.

7. Qi Xiao, Jinrong Feng, Jiawen Li, Yi Liu, Dan Wang, Shan Huang*. Ratiometric electrochemical biosensor for ultrasensitive and highly selective detection of K-ras gene via exonuclease III-assisted target recycling and rolling circle amplification strategies. Analytical Methods 2019, 11, 4146−4156.

8. Shan Huang, Haimei Li, Yi Liu, Yu Liang, Wei Su, Qi Xiao*. Comparable investigation of in vitro interactions between three ruthenium(II) arene complexes with curcumin analogs and ctDNA. Polyhedron 2019, 167, 5161.

2018

1. Shan Huang, Erli Yang, Yi Liu, Jiandong Yao, Wei Su, Qi Xiao*. Low-temperature rapid synthesis of nitrogen and phosphorus dual-doped carbon dots for multicolor cellular imaging and hemoglobin probing in human blood. Sensors and Actuators B: Chemical 2018, 265, 326334. (中科院大类一区)

2. Shan Huang, Erli Yang, Jiandong Yao, Yi Liu, Qi Xiao*. Carbon dots doped with nitrogen and boron as ultrasensitive fluorescent probes for determination of α-glucosidase activity and its inhibitors in water samples and living cells. Microchimica Acta 2018, 185, 394. (中科院大类二区)

3. Shan Huang, Mengmeng Feng, Jiawen Li, Yi Liu, Qi Xiao*. Voltammetric determination of attomolar levels of a sequence derived from the genom of hepatitis B virus by using molecular beacon mediated circular strand displacement and rolling circle amplification. Microchimica Acta 2018, 185, 206. (中科院大类二区)

4. Shan Huang, Erli Yang, Jiandong Yao, Yi Liu, Qi Xiao*. Red emission nitrogen, boron, sulfur co-doped carbon dots for “on-off-on” fluorescent mode detection of Ag+ ions and L-cysteine in complex biological fluids and living cells. Analytica Chimica Acta 2018, 1035, 192202. (中科院大类二区)

5. Qi Xiao, Jinrong Feng, Jiawen Li, Mengmeng Feng, Shan Huang*. A label-free and ultrasensitive electrochemical aptasensor for lead(II) using a N,P dual-doped carbon dot-chitosan composite as a signal-enhancing platform and thionine as a signaling molecule. Analyst 2018, 143, 47644773. (中科院大类二区)

6. Shan Huang, Yu Liang, Jianguo Cui*, Jiangning Xie, Yi Liu, Baoqing Hu, Qi Xiao*. Comparative investigation of binding interactions with three steroidal derivatives of d(GGGT)4 G-quadruplex aptamer. Steroids 2018, 132, 4655.

7. Qi Xiao, Mengmeng Feng, Yi Liu, Shuangyan Lu, Yingzi He, Shan Huang*. The graphene/polypyrrole/chitosan-modified glassy carbon electrode for electrochemical nitrite detection. Ionics 2018, 24, 845859.

8. Shan Huang, Erli Yang, Lumin Wang, Yi Liu, Jiangning Xie, Baoqing Hu, Qi Xiao*. Carbon dots-based frequency-doubling scattering probes for the ultrasensitive and highly selective determination of hemoglobin. Analytical Methods 2018, 10, 891899.

9. Qi Xiao, Yu Liang, Yi Liu, Shuangyan Lu, Shan Huang*. Comparison of molecular interactions of Ag2Te and CdTe quantum dots with human serum albumin by spectroscopic approaches. Luminescence 2018, 33, 181189.

2017

1. Shan Huang, Lumin Wang, Chusheng Huang, Wei Su, Qi Xiao*. Label-free and ratiometric fluorescent nanosensor based on amino-functionalized graphene quantum dots coupling catalytic G-quadruplex/hemin DNAzyme for ultrasensitive recognition of human telomere DNA. Sensors and Actuators B: Chemical 2017, 245, 648−655. (中科院大类一区)

2. Qi Xiao, Yu Liang, Fawei Zhu, Shuangyan Lu, Shan Huang*. Microwave-assisted one-pot synthesis of highly luminescent N-doped carbon dots for cellular imaging and multi-ion probing. Microchimica Acta 2017, 184, 24292438. (中科院大类二区)

3. Shan Huang, Jiangning Xie, Jianguo Cui*, Liang Liu, Yu Liang, Yi Liu, Qi Xiao*. Comparative investigation of binding interactions between three steroidal compounds and human serum albumin: Multispectroscopic and molecular modeling techniques. Steroids 2017, 128, 136146.

4. Shan Huang, Jiangning Xie, Wei Su, Yi Liu, Xiaohui Wang, Baoqing Hu, Qi Xiao*. Comparative investigation of interactions between two ruthenium(II) arene PTA type complexes with curcuminoid ligands and human serum albumin. Journal of Organometallic Chemistry 2017, 853, 8192.

5. Qi Xiao, Shuangyan Lu, Chusheng Huang, Wei Su, Shuyu Zhou, Jiarong Sheng, Shan Huang*. An electrochemical chiral sensor based on aminofunctionalized graphene quantum dots/βcyclodextrin modified glassy carbon electrode for enantioselective detection of tryptophan isomers. Journal of the Iranian Chemical Society 2017, 14, 1957–1970.

2016

1. Shan Huang, Shuangyan Lu, Chusheng Huang, Jiarong Sheng, Lixia Zhang, Wei Su, Qi Xiao*. An electrochemical biosensor based on single-stranded DNA modified gold electrode for acrylamide determination. Sensors and Actuators B: Chemical 2016, 224, 22−30. (中科院大类一区)

2. Shan Huang, Lumin Wang, Chusheng Huang, Wei Su, Qi Xiao*. Amino-functionalized graphene quantum dots based ratiometric fluorescent nanosensor for ultrasensitive and highly selective recognition of horseradish peroxidase. Sensors and Actuators B: Chemical 2016, 234, 255263. (中科院大类一区)

3. Shan Huang, Lumin Wang, Chusheng Huang, Baoqing Hu, Wei Su, Qi Xiao*. Graphene quantum dot coupled with gold nanoparticle based off-on fluorescent probe for sensitive and selective detection of L-cysteine. Microchimica Acta 2016, 183, 18551864. (中科院大类二区)

4. Shan Huang, Hangna Qiu, Yi Liu, Chusheng Huang, Jiarong Sheng, Jianguo Cui, Wei Su, Qi Xiao*. Systematical investigation of in vitro interaction of InP/ZnS quantum dots with human serum albumin by multispectroscopic approach. Colloids and Surfaces B: Biointerfaces 2016, 148, 165172. (中科院大类二区)

5. Shan Huang, Shushu Peng, Wei Su, Zhaofeng Tang, Jianguo Cui, Chusheng Huang, Qi Xiao*. In vitro interaction investigation between three Ru(II) arene complexes and human serum albumin: Structural influences. RSC Advances 2016, 6, 4704347054.

6. Shan Huang, Hangna Qiu, Jiangning Xie, Chusheng Huang, Wei Su, Baoqing Hu, Qi Xiao*. Systematical investigation of in vitro molecular interaction between fluorescent carbon dots and human serum albumin. RSC Advances 2016, 6, 4453144542.

7. Qi Xiao, Shuangyan Lu, Chusheng Huang, Wei Su, Shan Huang*. Novel N-doped carbon dots/β-cyclodextrin nanocomposites for enantioselective recognition of tryptophan enantiomers. Sensors 2016, 16, 1874.

8. Shan Huang, Shushu Peng, Fawei Zhu, Xiaolin Lei, Qi Xiao*, Wei Su, Yi Liu, Chusheng Huang, Lixia Zhang. Multispectroscopic investigation of the interaction between two Ruthenium(II) arene complexes of curcumin analogs and human serum albumin. Biological Trace Element Research 2016, 169, 189−203.

9. Shan Huang, Yu Liang, Chusheng Huang, Wei Su, Xiaolin Lei, Yi Liu, Qi Xiao*. Systematical investigation of binding interaction between novel ruthenium(II) arene complex with curcumin analogs and ctDNA. Luminescence 2016, 31, 13841394.

2015

1. Shan Huang, Hangna Qiu, Shuangyan Lu, Fawei Zhu, Qi Xiao*. Study on the molecular interaction of graphene quantum dots with human serum albumin: Combined spectroscopic and electrochemical approaches. Journal of Hazardous Materials 2015, 285, 1826. (中科院大类一区)

2. Shan Huang, Lumin Wang, Chusheng Huang, Jiangning Xie, Wei Su, Jiarong Sheng, Qi Xiao*. A carbon dots based fluorescent probe for selective and sensitive detection of hemoglobin. Sensors and Actuators B: Chemical 2015, 221, 12151222. (中科院大类一区)

3. Shan Huang, Hangna Qiu, Fawei Zhu, Shuangyan Lu, Qi Xiao*. Graphene quantum dots as on-off-on fluorescent probes for chromium(VI) and ascorbic acid. Microchimica Acta 2015, 182, 17231731. (中科院大类二区)

4. Shan Huang, Shuangyan Lu, Chusheng Huang, Jiarong Sheng, Wei Su, Lixia Zhang, Qi Xiao*. Sensitive and selective stripping voltammetric determination of copper(II) using a glassy carbon electrode modified with amino-reduced graphene oxide and β-cyclodextrin. Microchimica Acta 2015, 182, 2529−2539. (中科院大类二区)

5. Shan Huang, Hangna Qiu, Yi Liu, Chusheng Huang, Jiarong Sheng, Wei Su, Qi Xiao*. Molecular interaction investigation between three CdTe:Zn2+ quantum dots and human serum albumin: A comparative study. Colloids and Surfaces B: Biointerfaces 2015, 136, 955−962. (中科院大类二区)

6. Shan Huang, Lumin Wang, Fawei Zhu, Wei Su, Jiarong Sheng, Chusheng Huang, Qi Xiao*. A ratiometric nanosensor based on fluorescent carbon dots for label-free and highly selective recognition of DNA. RSC Advances 2015, 5, 4458744597.

7. Shan Huang, Fawei Zhu, Qi Xiao*, Yu Liang, Quan Zhou, Wei Su*. Thermodynamic investigation of the interaction between the [(η6-p-cymene)Ru(benzaldehyde-N4-phenylthiosemicarbazone)Cl]Cl anticancer drug and ctDNA: multispectroscopic and electrochemical studies. RSC Advances 2015, 5, 4288942902.

8. Shan Huang, Fawei Zhu, Quanquan Qian, Qi Xiao*, Wei Su*. Thermodynamic investigation of interaction between [(η6-p-Cymene)RuII(Acetone-N4-Phenylthiosemicarbazone)Cl]Cl anticancer drug and human serum albumin: Spectroscopic and electrochemical studies. Biological Trace Element Research 2015, 164, 150161.

2014

1. Shan Huang*, Fawei Zhu, Hangna Qiu, Qi Xiao*, Quan Zhou, Wei Su*, Baoqing Hu. A sensitive quantum dots-based “OFF-ON” fluorescent sensor for Ruthenium anticancer drugs and ctDNA. Colloids and Surfaces B: Biointerfaces 2014, 117, 240−247. (中科院大类二)

2. Shan Huang, Fawei Zhu, Qi Xiao*, Wei Su, Jiarong Sheng, Chusheng Huang, Baoqing Hu. A CdTe/CdS/ZnS core/shell/shell QDs-based “OFF-ON” fluorescent biosensor for sensitive and specific determination of L-ascorbic acid. RSC Advances 2014, 4, 46751−46761.

3. Shan Huang, Fawei Zhu, Qi Xiao*, Quan Zhou, Wei Su*, Hangna Qiu, Baoqing Hu, Jiarong Sheng, Chusheng Huang. Combined spectroscopy and cyclic voltammetry investigates the interaction between [(η6-p-cymene)Ru(benzaldehyde-N(4)-phenylthiosemicarbazone)Cl]Cl anticancer drug and human serum albumin. RSC Advances 2014, 4, 3628636300.

2013

1. Shan Huang, Guozhu Chen, Mohamed Chaker, Tsuneyuki Ozaki, Peter Tijssen, Dongling Ma*. Fluorescent-magnetic multifunctional nanoparticles for imaging and drug delivery. Reviews in Nanoscience and Nanotechnology 2013, 2, 346−364. (Invited Review)

2. Shan Huang, Qi Xiao*, Wei Su, Peiyuan Li, Jianqiang Ma, Zhike He. Simple and sensitive determination of papain by resonance light-scattering with CdSe quantum dots. Colloids and Surfaces B: Biointerfaces 2013, 102, 146−151. (中科院大类二)

3. Qi Xiao, Shan Huang*, Wei Su, Peiyuan Li, Jianqiang Ma, Fenping Luo, Jing Chen, Yi Liu*. Systematically investigations of conformation and thermodynamics of HSA adsorbed to different sizes of CdTe quantum dots. Colloids and Surfaces B: Biointerfaces 2013, 102, 76−82. (中科院大类二)

4. Qi Xiao, Shan Huang*, Wei Su, Peiyuan Li, Yi Liu*. Evaluate the potential toxicity of quantum dots on bacterial metabolism by microcalorimetry. Thermochimica Acta 2013, 552, 98−105.

5. Qi Xiao, Hangna Qiu, Shan Huang*, Chusheng Huang, Wei Su, Baoqing Hu, Yi Liu*. Systematic investigation of interactions between papain and MPA-capped CdTe quantum dots. Molecular Biology Reports 2013, 40, 5781−5789.

6. Shan Huang, Hangna Qiu, Qi Xiao*, Chusheng Huang, Wei Su, Baoqing Hu. A simple QD−FRET bioprobe for sensitive and specific detection of hepatitis B virus DNA. Journal of Fluorescence 2013, 23, 1089−1098.

7. Shan Huang, Jianqiang Ma, Qi Xiao*, Mingyue Dong, Xuehua Li, Qiuling Luo. Direct determinaiton of isocarbophos by using oil soluble CdSe quantum dots as fluorescent probe. Spectroscopy and Spectral Analysis 2013, 33, 28532857.

2012

1. Qi Xiao, Shan Huang*, Wei Su, WH Chan*, Yi Liu*. Facile synthesis and characterization of highly fluorescent and biocompatible N-acetyl-L-cysteine capped CdTe/CdS/ZnS core/shell/shell quantum dots in aqueous phase. Nanotechnology 2012, 23, 495717. (中科院大类二)

2. Qi Xiao, Shan Huang*, Jianqiang Ma, Wei Su, Peiyuan Li, Jianguo Cui, Yi Liu*. Systematically investigation of interactions between BSA and different charge-capped CdSe/ZnS quantum dots. Journal of Photochemistry and Photobiology A: Chemistry 2012, 249, 53−60.

3. Qi Xiao, Shan Huang*, Wei Su, Peiyuan Li, Zuocui Liang, Jianzhen Ou, Jianqiang Ma, Yi Liu*. Evaluate the potential environmental toxicity of quantum dots on ciliated protozoa by microcalorimetry. Thermochimica Acta 2012, 547, 62−69.

4. Qi Xiao, Ting Qiu, Shan Huang, Yi Liu*, Zhike He*. Preparation and biological effect of nucleotide capped CdSe/ZnS quantum dots on Tetrahymena Thermophila. Biological Trace Element Research 2012, 147, 346353.

2011年及以前

1. Shan Huang, Qi Xiao, Zhike He*, Yi Liu, Philip Tinnefeld, Xiongrui Su, Xiaoniu Peng. A high sensitive and specific QDs FRET bioprobe for MNase. Chemical Communications 2008, 45, 59905992. (中科院大类一)

2. Shan Huang, Qi Xiao, Ran Li, Hongliang Guan, Jiang Liu, Xiaorong Liu, Zhike He*, Yi Liu. A simple and sensitive method for L-cysteine detection based on the fluorescence intensity increment of quantum dots. Analytica Chimica Acta 2009, 645, 73−78. (中科院大类二)

3. Qi Xiao, Bo Zhou, Shan Huang, Fangfang Tian, Hongliang Guan, Yushu Ge, Xiaorong Liu, Zhike He, Yi Liu*. Direct observation of the binding process between protein and quantum dots by in-situ surface plasmon resonance measurements. Nanotechnology 2009, 20, 325101. (中科院大类二)

4. Yong Lei, Qi Xiao, Shan Huang, Wansu Xu, Zhe Zhang, Zhike He, Yi Liu*, Fengjiao Deng*. Impact of CdSe/ZnS quantum dots on the development of zebrafish embryos. Journal of Nanoparticle Research 2011, 13, 68956906.

5. Qi Xiao, Shan Huang, Yushu Ge, Zhike He*, Yi Liu, Jiangong Liang. A novel fluorescent silver ion biosensor based on nucleic acid molecular "light switch". Journal of Fluorescence 2010, 20, 541−549.

6. Qi Xiao, Shan Huang, Yi Liu*, Fangfang Tian, Juncheng Zhu. Thermodynamics, Conformation and active sites of the binding of Zn-Nd hetero-bimetallic schiff base to bovine serum albumin. Journal of Fluorescence 2009, 19, 317326.

7. Qi Xiao, Shan Huang, Zude Qi, Bo Zhou, Zhike He, Yi Liu*. Conformation, thermodynamics and stoichiometry of HSA adsorbed to colloidal CdSe/ZnS quantum dots. BBA-Proteins and Proteomics 2008, 1784, 10201027.

8. Shan Huang, Qi Xiao, Zhike He*, Yi Liu. Resonance light scattering method for the determinaiton of lysozyme using CdSe quantum dots as probe. Chemical Journal of Chinese Universities-Chinese 2009, 30, 1951−1955.

9. Shan Huang, Zhike He*. Quantum dots-ssDNA-fluorescent dye conjugates as bioprobes for specific and sensitive detection of DNase. Luminescence 2008, 23, 73.

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